The most current update of the ASA's Difficult Airway Guidelines.

Abstaining from perioperative bridging was noninferior to bridging with LMWH in subjects with low and moderate risk atrial fibrillation taking warfarin, and decreased rates of bleeding.

In an international trial with more than 6,000 subjects, intensive glucose control (81 to 108 mg/dL) resulted in increased mortality compared to a more liberal range of 180 mg/dL or less.

The first publication documenting our modern conception of CPR.

The first publication of the Apgar scoring system.

The first published report of the use of general anesthesia.

Goal-directed hemodynamic therapy (utilizing esophageal doppler monitoring) reduces postop complications and hospital length of stay in patients undergoing major elective surgery.

In elderly patients undergoing hip fracture surgery, the use of regional anesthesia without sedation did not decrease the rate of postoperative delirium compared to general anesthesia.

A BIS-guided anesthetic protocol was not superior to an end-tidal anesthetic-agent concentration protocol for reducing the incidence of awareness.

BIS-guided anesthesia reduces the risk of awareness in at-risk adults undergoing general anesthesia with muscle relaxant.

In high-risk patients undergoing major abdominal surgery, a restrictive fluid regimen did not improve the rate of disability-free survival but did result in increased acute kidney injury.

In ICU patients, the use of balanced crystalloids resulted in a reduction of death and kidney dysfunction as compared to the use of normal saline.

In patients with ALI/ARDS, lower tidal volume ventilation (6ml/kg) decreases mortality and increases the number of ventilator-free days.

Preoperative initiation of metoprolol results in a decrease in the rate of perioperative MI but an increase in the rates of stroke and death.

Ondansetron, dexamethasone, and droperidol reduce the risk of PONV by similar amounts. These medications and other interventions should be used based on the individual patient's preoperative risk.

In patients with acute lung injury, PAC-guided therapy did not improve survival or lung or kidney function versus CVC-guided therapy.

An expansive paper on the spread of local anesthetics in the epidural space. Showed that spread is effected by multiple factors, including age, height, posture, pregnancy, and local anesthetic concentration.

Early goal-directed therapy reduces mortality in patients with septic shock.

An international, multicenter, RCT that showed that the age of transfused red blood cells did not affect 90-day mortality in critically ill patients.

In high-risk patients undergoing surgical repair of hip fracture, a RBC transfusion threshold of 8 g/dL resulted in similar rates of mortality and ambulatory function as a higher threshold of 10 g/dL.

The administration of tranexamic acid to bleeding trauma patients reduces mortality.