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The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting: A Meta-Analysis
May
, 2016
Journal: Anesthesia and Analgesia
PMID:
26991615
Type of study: Meta-analysis
Hypothesis: To investigate the ability of gabapentin to prevent PONV.
Methods: Meta-analysis of 44 trials.
Results: Preoperative gabapentin is associated with a reduced incidence of PONV.
Strengths: Examined multiple trials
Weaknesses: Cannot compare the effectiveness of gabapentin against other anti-emetics, unclear mechanism of action
Key Point: Preoperative gabapentin is associated with a lower incidence of PONV.
Anesth Analg. 2016 Apr;122(4):976-85.
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